Treatment of locally advanced or metastatic non-small cell lung cancer patients with anaplastic lymphoma kinase (ALK) positive.

Acute myeloid leukemia

Bone marrow fibrosis,vitiligo

Urticaria, rhinitis

Clinical isolated syndrome,multiple sclerosis

Heavy metal poisoning,Wilson's disease

Type 2 diabetes

For the treatment of schizophrenia and bipolar disorder depressive episodes